It is important that clients understand how valuable these pictures are to you. Don't spring surprises on them. Let them know in advance what you plan to do. Once the job is completed, excuses are heard about inconvenience, privacy, etc. Let them know how relevant this is to your career. I know many designers include this request in their contracts.
While some clients insist on being there on the "shoot day", only you can judge the wisdom of this. Some enjoy watching and like to help; but, many are annoyed at some of the "artistic turmoil" that goes into this event. Furniture is moved; things are added and subtracted; some clients are upset with these procedures. If you anticipate a problem, see if the shoot can be done (with their permission) when the client is not at home. All of this is necessary to reorganize the room for "its portrait". We have two eyes and a brain. We can walk into a room and feel a space; what the space says to you. We can understand that; unfortunately, the camara cannot. It only sees - it does not feel.
Therefore, our job is to make the camera see what we feel. Conversely, what might appear pleasing to our eyes may just look like clutter to the lens.
On this special day you might consider bringing in fresh flowers, additional artwork, etc. Whatever it takes to fulfill your design concept - DO IT! However, don't go overboard. Remember your original design conception.